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• Sonothrombolysis
• Drug/Marker Delivery
• Observations of Cell - Bubble - Ultrasound Interaction
• Gene Transfer

Date

Category

Title

Researchers

PubMed

Detail

1995-01-25

Drug/Marker Delivery

Sonoporation Of Cultured Cells In The Rotating Tube Exposure System

Douglas L. Miller, Shiping Bao, James E. Morris

[LINK]

1997-04-01

Observations of Cell - Bubble - Ultrasound Interaction

Interactions Between Microbubbles And Ultrasound: In Vitro And In Vivo Observations

Kevin Wei, MD, Danny M. Skyba, Ph.D, Christian Firschke, MD, Ananda R. Jayaweera, Ph.D, Jonathan R. Lindner, MD, Sanjiv Kaul, MD, FACC

[LINK]

1998-08-17

Drug/Marker Delivery

Micellar Delivery Of Doxorubicin And Its Paramagnetic Analog, Ruboxyl, To Hl-60 Cells: Effect Of Micelle Structure And Ultrasound On The Intracellular Drug Uptake

Natalya Y. Rapoport, James N. Herron, William G. Pittb, Lubov Pitina

[LINK]

1998-08-19

Drug/Marker Delivery

Delivery Of Colloidal Particles And Red Blood Cells To Tissue Through Microvessel Ruptures Created By Targeted Microbubble Destruction With Ultrasound

Richard J. Price, PhD, Danny M. Skyba, PhD, Sanjiv Kaul, MD, Thomas C. Skalak, PhD

[LINK]

2001-07-11

Observations of Cell - Bubble - Ultrasound Interaction

“Stable” Inertial Cavitation

Charles C. Church, Edwin L. Carstensen

[LINK]

2001-09-26

Observations of Cell - Bubble - Ultrasound Interaction

Reparable Sonoporation Generated By Microstreaming

Junru Wu, Joel P. Ross, Jen-Fu Chiu

[LINK]

2002-01-03

Gene Transfer

Local Delivery Of Plasmid Dna Into Rat Carotid Artery Using Ultrasound

Yoshiaki Taniyama, Katsuro Tachibana, Kazuya Hiraoka, Tsunetatsu Namba, Keita Yamasaki, Naotaka Hashiya, Motokuni Aoki, Toshio Ogihara, Kaneda Yasufumi, Ryuichi Morishita

[LINK]

2002-03-27

Gene Transfer

Dna-Loaded Albumin Microbubbles Enhance Ultrasound Mediated Transfection In Vitro

Peter A. Frenkel, Shuyuan Chen, To Thai, Ralph V. Shohet, Paul A. Grayburn

[LINK]

2002-05-01

Drug/Marker Delivery

An Investigation Of The Role Of Cavitation In Low-Frequency Ultrasound-Mediated Transderma Drug Transport

Hua Tang, Chiao Chun Joanne Wang, Daniel Blankschtein, Robert Langer

[LINK]

2002-08-16

Drug/Marker Delivery

Drug Delivery In Pluronic Micelles: Effect Of High-Frequency Ultrasound On Drug Release From Micelles And Intracellular Uptake

Alexandre Marin, Hao Sun, Ghaleb A. Husseini, William G. Pitt, Douglas A. Christensen, Natalya Y. Rapoport

[LINK]

2002-08-21

Observations of Cell - Bubble - Ultrasound Interaction

Microbubbles Induce Renal Hemorrhage When Exposed To Diagnostic Ultrasound In Anesthetized Rats

James H. Wible, Jr., Karen P. Galen, Jolette K. Wojdyla, Michael S. Hughes, Alexander L. Klibanov, Gary H. Brandenburger

[LINK]

2002-08-30

Drug/Marker Delivery

Investigating The Mechanism Of Acoustically Activated Uptake Of Drugs From Pluronic Micelles

Ghaleb A Husseini, Christopher M Runyan, William G Pitt

[LINK]

2002-11-01

Observations of Cell - Bubble - Ultrasound Interaction

Characterization Of Ultrasound-Mediated Cellular Effects

Robin K Schlicher, Monali Desai, Mark R. Prausnitz, Robert P. Apkarian

2002-12-23

Observations of Cell - Bubble - Ultrasound Interaction

The Pulse Length-Dependence Of Inertial Cavitation Dose And Hemolysis

Wen-Shiang Chen, Andrew A. Brayman, Thomas J. Matula, Lawrence A. Crum, Morton W. Miller

[LINK]

2003-05-29

Observations of Cell - Bubble - Ultrasound Interaction

Contrast Agent Bubble And Erythrocyte Behavior In A 1.5-Mhz Standing Ultrasound Wave

Sanjay Khanna, Nazar N. Amso, Sharon J. Paynter, W. Terence Coakley

[LINK]

2003-08-07

Gene Transfer

Microbubble-Enhanced Sonoporation: Efficient Gene Transduction Technique For Chick Embryos

Sho Ohta, Kentaro Suzuki, Katsuro Tachibana, Gen Yamada

[LINK]

2004-01-15

Observations of Cell - Bubble - Ultrasound Interaction

Ultrasound-Induced Cell Membrane Porosity

Cheri X. Deng, Fred Sieling, Hua Pan, Jianmin Cui

[LINK]

2004-04-01

Drug/Marker Delivery

Radionuclide Tumour Therapy With Ultrasound Contrast Microbubbles

Annemieke van Wamel, Ayache Bouakaz, Folkert ten Cate, Nico de Jong

[LINK]

2004-07-27

Observations of Cell - Bubble - Ultrasound Interaction

Micromanipulation Of Endothelial Cells: Ultrasound -Microbubble- Cell Interaction

Annemieke van Wamel, Ayache Bouakaz, Michel Versluis, Nico de Jong

[LINK]

2004-11-08

Drug/Marker Delivery

Ultrasound-Enhanced Transcorneal Drug Delivery

V. Zderic, J.I. Clark, R.W. Martin, S. Vaezy

[LINK]

2005-02-01

Gene Transfer

Optimal Drug And Gene Delivery In Cancer Cells By Ultrasound Induced Cavitation

Irina V. Larina, B. Mark Evers, Rinat O. Esenaliev

[LINK]

2005-05-01

Drug/Marker Delivery

Spatially Controlled Sonoporation Of Prostate Cancer Cells Via Ultrasound Activated Microbubble Cavitation

P.A. Prentice, D. McLean, A. Cuschieri, K. Dholakia, P.A.Campbell

2005-06-21

Drug/Marker Delivery

Stabilization And Activation Of Pluronic Micelles For Tumor-Targeted Drug Delivery

Natalya Rapoport, Zhonggao Gao, Anne Kennedy

2005-06-22

Gene Transfer

Microbubble-Enhanced Ultrasound For Vascular Gene Delivery

A Lawrie, A F Brisken, S E Francis, D C Cumberland, D C Crossman, C M Newman

[LINK]

2005-06-23

Observations of Cell - Bubble - Ultrasound Interaction

Microbubble Enhanced Threshold Reductions For Tissue Damage Using High Intensity Ultrasound

Binh C. Tran, Jongbum Seo, J. Brian Fowlkes, Charles A. Cain

2005-06-24

Drug/Marker Delivery

Ultrasound-Enhanced Drug Delivery For Efficient Cancer Therapy

I.V. Larina, B.M. Evers, C. Bartels, T.V. Ashitkov, K.V. Larin, R.O. Esenaliev

[LINK]

2005-06-24

Drug/Marker Delivery

Effects Of Diagnostic Ultrasound Parameters On Molecular Uptake And Cell Viability

Annemieke van Wamel, Ayache Bouakaz, Folkert ten Cate, Nico de Jong

2005-06-25

Gene Transfer

Gene Transfer With Echo-Enhanced Contrast Agents: Comparison Between Albunex, Optison, And Levovist In Mice — Initial Results

Tieli Li, Katsuro Tachibana, Motomu Kuroki, Masahide Kuroki

[LINK]

2005-06-26

Drug/Marker Delivery

Microbubble Potentiated Changes In Cell Permeability And Viability

Raffi Karshafian, Peter D. Bevan, Peter N. Burns

2005-06-27

Drug/Marker Delivery

Plasma Membrane Poration Induced By Ultrasound Exposure: Implication For Drug Delivery

Sophie Mehier-Humbert, Thierry Bettinger, Feng Yan, Richard H. Guy

[LINK]

2005-06-27

Drug/Marker Delivery

Sonoporation With Doxorubicin Enhances Suppression Of Intimal Hyperplasia In A Vein Graft Model

Yoshimasa Mizuno, M.D., Hisashi Iwata, M.D., Ph.D., Hisato Takagi, M.D., Ph.D., Shoji Yoshikawa, Ph.D., Yukio Umeda, M.D., Ph.D., Yukihiro Matsuno, M.D., Ph.D., Yoshio Mori, M.D., Ph.D., Hirofumi Takemura, M.D., Ph.D.

[LINK]

2005-06-27

Drug/Marker Delivery

Drug Delivery In Tumors By Ultrasound Combined With Nanoparticles

Irina V. Larina, B. Mark Evers, Taras V. Ashitkov, Christian Bartels, Kirill V. Larin, Rinat O. Esenaliev

2005-06-27

Gene Transfer

Ultrasound-Mediated Gene Delivery: Kinetics Of Plasmid Internalization And Gene Expression

Sophie Mehier-Humbert, Thierry Bettinger, Feng Yan, Richard H. Guy

[LINK]

2005-06-27

Observations of Cell - Bubble - Ultrasound Interaction

Real Time Observation Of The Ultrasound Stimulated Disintegration Of Optically Trapped Microbubbles In Proximity To Biological Cells, International Society For Optical Engineering

Paul Campbell, Alfred Cuschieri, Kishan Dholakia, Michael P. MacDonald, Paul Prentice

2005-06-28

Drug/Marker Delivery

Effect Of Anticancer Drug On The Cell Sensitivity To Ultrasound In Vitro And In Vivo

Pavel P. Kamaev, Natalya Y. Rapoport

2005-06-28

Drug/Marker Delivery

Ultrasound-Enhanced Localized Chemotherapy Of Drug-Sensitive And Multidrug Resistant Tumors

Natalya Y. Rapoport, Zhonggao Gao, Pavel Kamaev, Douglas A. Christensen

2005-06-28

Drug/Marker Delivery

Ultrasound-Mediated Therapies Using Receptor-Targeted Nanodroplets

P. Schumann, B.S., R. LaBell, Ph.D, K. Penrose, A. Kerschen, B.S., E. Unger, M.D., T. Matsunaga, Pharm.D., Ph.D, R. Zutshi, Ph.D.

2005-06-28

Gene Transfer

Intracellular Delivery Of Peptides And Sirnas Using Microbubble Enhanced Focused Ultrasound

Manabu Kinoshita M.D., Kullervo Hynynen Ph.D.

2005-06-28

Gene Transfer

Efficient Gene Delivery To Pancreatic Islets With Ultrasonic Microbubble Destruction Technology

Shuyuan Chen, Jia-huan Ding, Raffi Bekeredjian, Bing-zhi Yang, Ralph V. Shohet, Stephen A. Johnston, Hans E. Hohmeier, Christopher B. Newgard, Paul A. Grayburn

[LINK]

2005-06-28

Gene Transfer

Targeted Vascular Delivery Of Antisense Molecules Using Intravenous Microbubbles

Thomas R Porter , Feng Xie , Derek Knapp , Patrick Iversen , Luis A Marky , Jeane M Tsutsui , Souvik Maiti , John Lof , Stanley J Radio , Nicholas Kipshidze

[LINK]

2005-06-28

Observations of Cell - Bubble - Ultrasound Interaction

Microbubbles Reforming Endothelium

Annemieke van Wamel, Klazina Kooiman, Miranda Harteveld, Marcia Emmer, Folkert J. ten Cate, Michel Versluis, Nico de Jong

2005-06-28

Observations of Cell - Bubble - Ultrasound Interaction

The Effect Of Acoustic Exposure Parameters On Cell Membrane Permeabilisation By Ultrasound And Microbubbles

Raffi Karshafian, Peter D. Bevan, Sanya Samac, Peter N. Burns

2005-06-28

Observations of Cell - Bubble - Ultrasound Interaction

Induction Of Apoptosis In Vivo In The Rabbit Brain With Focused Ultrasound

Natalia I. Vykhodtseva, Nathan McDannold, Kullervo Hynynen

[LINK]

2005-06-28

Observations of Cell - Bubble - Ultrasound Interaction

Noninvasive Blood-Brain Barrier Opening In Live Mice

James J. Choi, Mathieu Pernot, Scott Small, Elisa E. Konofagou

[LINK]

2005-06-28

Observations of Cell - Bubble - Ultrasound Interaction

Development Of Microcapsules For Shock Wave Dds And Angiogenesis Using Shock Waves

M. Tamagawa, I. Yamanoi, S. Iwakura

2005-06-28

Observations of Cell - Bubble - Ultrasound Interaction

Multiphoton Imaging Of Ultrasound Bioeffects In The Murine Brain

Scott Raymond, Jesse Skoch, Brian Bacskai, Kullervo Hynynen

2005-06-28

Sonothrombolysis

Ultrasound Augmented Thrombolysis, From Test Tubes To Clinical Applications

William C. Culp

2005-06-28

Sonothrombolysis

Sonothrombolysis In Acute Ischemic Stroke For Patients Ineligible For Rt-Pa

J. Krejza, J. B. Weigele, R. Alokaili, M. Arkuszewski, R. W. Hurst, Seidel Günter, Jürgen Eggers

[LINK]

2005-06-28

Sonothrombolysis

Effects Of Simultaneous Application Of Ultrasound And Microbubbles On Intracerebral Hemorrhage In An Animal Model

Mark Stroick, Angelika Alonso, Marc Fatar, Martin Griebe, Stefan Kreisel, Rolf Kern, Emmanuel Gaud, Marcel Arditi, Michael Hennerici, Stephen Meairs

[LINK]

2005-06-29

Drug/Marker Delivery

Local Delivery Of Cytotoxic Agents To Tumours By Focused Sonoporation

K Iwanaga, K Tominaga, K Yamamoto, M Hau, H Maeda, S Akifua, T Tsujisawa, T Okinaga, J Fukada, T Nishiara

[LINK]

2005-06-29

Drug/Marker Delivery

Multifunctional Nanoparticles For Combining Ultrasonic Tumor Imaging And Targeted Chemotherapy

Natalya Rapoport , Zhonggao Gao, Anne Kennedy

[LINK]

2005-06-29

Drug/Marker Delivery

Ultrasound Microbubble Contrast Agents: Fundamentals And Application To Gene And Drug Delivery

Ferrara Katherine, Pollard Rachel, Borden Mark,

[LINK]

2005-06-29

Drug/Marker Delivery

Effective Tumor Treatment Using Optimzed Ultrasound-Mediated Delivery Of Bleomycin

John O. Larkin, Garrett D. Casey, Mark Tangney, James Cashman, Chris G. Collins, Declan M. Soden, Gerald C. O’Sullivan

[LINK]

2005-06-29

Drug/Marker Delivery

Sonoporation Is An Efficient Tool For Intracellular Fluorescent Dextran Delivery And One-Step Double-Crossover Mutant Construction In Fusobacterium Nucleatum

Han Yiping W, Ikegami Akihiko, Chung Peter, Zhang Lei, Deng Cheri X

[LINK]

2005-06-30

Drug/Marker Delivery

Local And Reversible Opening Of The Bbb With Focused Ultrasound And Sonovue®

J. Jenne, A. Martin-Villalba, P. Flechsig, S. Kleber, A. Kuhn, M. Bock, P. Huber, B. Stieltjes

2005-06-30

Drug/Marker Delivery

Impact Of Focused Ultrasound-Enhanced Drug Delivery On Survival In Rats With Glioma

Lisa Treat, Yongzhi Zhang, Nathan McDannold, Kullervo Hynynen

2005-06-30

Gene Transfer

Ultrasound Gene Transfer Into Fibroblast Cells Using Microbubbles

Yoji Nakamura, Kiyoshi Yoshinaka, Yoichiro Matsumoto, Yuichi Tei

2005-06-30

Observations of Cell - Bubble - Ultrasound Interaction

Low-Intensity Ultrasound Inhibits Cancer Growth By Modifying Cell Cycle

Loreto Jr Feril , Katsuro Tachibana, Kazuki Yamaguchi, Yurika Ikeda-Dantsuji, Takashi Kondo

2005-06-30

Observations of Cell - Bubble - Ultrasound Interaction

Dependants Of Cavitation Bubble Resonance Size On Pressure Amplitude At Therapeutic Pressure Levels

Kelsey Carvell

2005-06-30

Observations of Cell - Bubble - Ultrasound Interaction

Development Of Hifu Therapy System For Lower Extremity Varicose Veins

Ryuhei Ohta

2005-06-30

Sonothrombolysis

A Pilot Randomized Clinical Safety Study Of Sonothrombolysis Augmentation With Ultrasound-Activated Perflutren-Lipid Microspheres For Acute Ischemic Stroke

Andrei V. Alexandrov, MD, Robert Mikulik, MD, Marc Ribo, MD, Vijay K. Sharma, MD, Annabelle Y. Lao, MD, Georgios Tsivgoulis, MD, Rebecca M. Sugg, MD, Andrew Barreto, MD, Paul Sierzenski, MD, Marc D. Malkoff, MD, James C. Grotta, MD

[LINK]

2005-06-30

Sonothrombolysis

Interactions Between Clot And Ultrasound: Better Blood Clot Break-Up With Bubbles

C. Holland, S. Datta, J. Meunier, G. Shaw

2005-06-30

Sonothrombolysis

Decreased Hemorrhage Using Microbubble Augmented Thrombolysis In Rabbits

W. Culp, R. Flores, J. Lowery, L. Hennings, P. Roberson, M. Borrelli

2005-10-27

Gene Transfer

Istu: T120 – Intracellular Delivery Of Peptides And Sirnas Using Microbubble Enhanced Focused Ultrasound.

Manabu Kinoshita, Kullervo Hynynen

2005-10-27

Sonothrombolysis

Istu T059: Nanobubble-Enhanced Sonothrombolysis: From Benchtop To Bedside

Evan Unger, MD, Terry Matsunaga, PharmD, PhD, Reena Zutshi, PhD, Rachel LaBell, Ph.D., Peter Tran, B.S., Andrei Alexandrov, MD

2005-11-17

Drug/Marker Delivery

Ultrasound Exposure Can Increase The Membrane Permeability Of Human Neutrophil Granulocytes Containing Microbubbles Without Causing Complete Cell Destruction

Grigorios Korosoglou, Stefan E. Hardt, Raffi Bekeredjian, Juergen Jenne, Mathias Konstantin, Marco Hagenmueller, Hugo A. Katus, Helmut Kuecherer

[LINK]

2006-02-01

Drug/Marker Delivery

Vibrating Microbubbles Poking Individual Cells: Drug Transfer Into Cells Via Sonoporation

Annemieke van Wamel, Klazina Kooiman, Miranda Harteveld, Marcia Emmer, Folkert J. ten Cate, Michel Versluis, Nico de Jong

[LINK]

2006-02-01

Gene Transfer

The Effects Of Albumin-Coated Microbubbles In Dna Delivery Mediated By Therapeutic Ultrasound

Maayan Duvshani-Eshet , Dan Adam, Marcelle Machluf

[LINK]

2006-03-01

Observations of Cell - Bubble - Ultrasound Interaction

The Relationship Of Acoustic Emission And Pulse-Repetition Frequency In The Detection Of Gas Body Stability And Cell Death

J. Brian Fowlkes, Douglas L. Miller , Stanley Samuel

[LINK]

2006-06-01

Drug/Marker Delivery

Acoustic Activation Of Targeted Liquid Perfluorocarbon Nanoparticles Does Not Compromise Endothelial Integrity

Neelesh R. Soman, Jon N. Marsh, Michael S. Hughes, Gregory M. Lanza, Samuel A. Wickline